Displaying items by tag: genetics

British scientists have identified a gene that doubles the risk of dying from Covid-19, opening up possibilities for targeted medicine and providing new insights into why some people are more susceptible to the disease than others. Researchers at Oxford University found that 60% of people with South Asian ancestry carry the high-risk gene. The discovery partly explains the high number of deaths seen in some British communities, and the effect of Covid in the Indian subcontinent. The scientists found that the increased risk is not because of a difference in genetic coding of the proteins, but because of differences in the DNA that makes a kind of ‘switch’ to turn a gene on. That genetic signal is likely to affect cells in the lung. The study shows that the way in which the lung responds to the infection is critical. This is important because most treatments have focused on changing the way in which the immune system reacts to the virus.

The Chinese government is obtaining blood samples from up to 70 million – 10% of all men and boys – as the high-tech surveillance state builds a ‘DNA Skynet’ of the country’s 700 million males. Any individual who refuses to give blood samples risks his family being barred from benefits such as travel, fast internet connection and hospital treatment. The powerful genetic mapping tool, which is being compiled from samples collected since 2017, will join up with China’s existing countrywide video-surveillance network. The system will be capable of tracking every male relative of any individual man just from a sample of his genetic material, such as skin or hair. Only 5-10% of the male population needs to be sampled in order to build a complete genetic map, because one sample unlocks the identity of all related males.